SMTP bounce code 5.2.1 indicates that the recipient's mailbox exists but has been disabled and is not accepting messages. This is a permanent failure (hard bounce), meaning the mailbox is intentionally disabled and should be removed from your mailing list.
The enhanced status code 5.2.1 follows the SMTP Enhanced Status Code format:
5 = Permanent failure (hard bounce)2 = Mailbox status (related to the recipient's mailbox)1 = Mailbox disabled, not accepting messagesWhen you receive a 5.2.1 bounce, it means the email address exists on the server, but the mailbox has been intentionally disabled by the email provider or the account owner. Unlike a deleted account (5.1.1), this mailbox may potentially be re-enabled in the future, but for email delivery purposes, it should be treated as a permanent failure.
Type : Hard bounce (permanent failure)Category : MailboxAction Required : Remove the email address from your mailing listAccount Suspension : The recipient's email account has been suspended by the email provider due to policy violationsAdministrative Disable : An administrator has disabled the mailbox (common in enterprise environments)Inactive Account : The account has been disabled due to prolonged inactivityPolicy Violation : The account was disabled due to violations of the email provider's terms of serviceAccount Closure Request : The user requested their account to be disabledBilling Issues : In paid email services, the account may be disabled due to non-paymentSecurity Measures : The account was disabled as a security precautionRemove from Mailing List : Immediately remove the email address from your active mailing listAdd to Suppression List : Add the address to a suppression list to prevent future sendsMonitor for Reactivation : While you should remove it from active lists, you can monitor if the mailbox becomes active again (though this is rare)Contact Recipient : If you have alternative contact information, reach out to verify if they want to re-enable the accountReview Your Practices : If you're seeing many 5.2.1 bounces, review your email practices to ensure you're not causing account suspensionsAutomated Removal : Set up automated processing to remove 5.2.1 bounces from your databaseSuppression List Management : Maintain a suppression list of disabled mailboxesLog Bounce Details : Track when and why mailboxes are disabled to identify patternsPeriodic Cleanup : Run periodic checks to clean up disabled mailboxes from your systemReactivation Monitoring : Optionally, implement a system to check if previously disabled mailboxes become active again5.1.1 (User Unknown) : The email address doesn't exist5.2.1 (Mailbox Disabled) : The email address exists but is disabled5.2.2 (Mailbox Full) : The mailbox exists but is full5.1.1 - User Unknown - Email address doesn't exist5.2.0 - Other Mailbox Status - Other mailbox-related issues5.2.2 - Mailbox Full (Permanent) - Mailbox permanently full4.2.1 - Mailbox Temporarily Disabled - Temporary mailbox unavailability550 5.2.1 Mailbox disabled
The recipient's mailbox has been disabled and is not accepting messages.
Gmail : "Mailbox disabled"Outlook/Hotmail : "550 5.2.1 Mailbox disabled"Enterprise : "Account suspended"Custom : "Mailbox not accepting messages"Remove Immediately : Treat 5.2.1 bounces as permanent failures and remove addresses immediatelyMaintain Suppression Lists : Keep a suppression list of disabled mailboxes to prevent future sendsMonitor Patterns : If you see many disabled mailboxes, review your email practicesRespect User Choices : If a user has disabled their account, respect that choiceDon't Retry : Unlike soft bounces, don't attempt to resend to disabled mailboxesClean Your Lists : Regularly clean your email lists to remove disabled mailboxesTrack Metrics : Monitor the percentage of disabled mailboxes in your lists to identify issues