SMTP bounce code 4.2.1 indicates that the recipient's mailbox is temporarily disabled and cannot accept new messages at this time. This is a soft bounce (temporary failure), meaning the mailbox should become available again and you should retry sending the email later.
The enhanced status code 4.2.1 follows the SMTP Enhanced Status Code format:
4 = Persistent transient failure (soft bounce)2 = Mailbox status (related to the recipient's mailbox)1 = Mailbox disabled (temporarily unavailable)When you receive a 4.2.1 bounce, it means the recipient's mailbox exists but is currently disabled or not accepting messages. Unlike hard bounces, this is typically a temporary condition that may resolve itself once the recipient re-enables their mailbox or the issue is resolved.
Type : Soft bounce (persistent transient failure)Category : MailboxAction Required : Retry sending after a delay (typically 24-48 hours)Account Suspension : The recipient's email account has been temporarily suspended by the email providerMaintenance : The mailbox is undergoing maintenance or updatesQuota Exceeded Temporarily : The mailbox has exceeded its quota and needs to be cleaned before accepting new messagesAccount Inactivity : The mailbox has been temporarily disabled due to inactivityAdministrative Action : An administrator has temporarily disabled the mailboxAuthentication Issues : Temporary authentication problems preventing mail deliveryServer Configuration : Temporary server configuration issues affecting the mailboxBilling Issues : Temporary suspension due to billing or payment issues (for paid email services)Retry Strategy : Implement an automated retry mechanism that attempts to resend the email after 24-48 hoursMonitor Retry Attempts : Don't retry indefinitely—if the mailbox remains disabled after 3-5 attempts, consider it a persistent issueContact Recipient : If possible, reach out to the recipient through alternative channels to inform them about the disabled mailboxSegment Affected Recipients : Create a segment for recipients with temporarily disabled mailboxes and pause sending until they re-enable their accountsReview Sending Frequency : Consider reducing email frequency for recipients who frequently have disabled mailboxesImplement Retry Logic : Set up exponential backoff retry logic for 4.2.1 bouncesTrack Retry Count : Monitor how many times you've retried sending to addresses with disabled mailboxesSet Retry Limits : Define a maximum number of retry attempts (typically 3-5) before marking as failedLog Bounce Patterns : Track which recipients frequently have disabled mailboxes to identify patternsAutomated Cleanup : After multiple failed retries, automatically pause sending to these addressesFor 4.2.1 bounces, implement a retry schedule:
First retry : 24 hours after initial bounceSecond retry : 48 hours after first retryThird retry : 72 hours after second retryFinal attempt : 1 week after third retryIf the mailbox remains disabled after all retry attempts, consider removing the address from your active list or marking it as inactive.
4.2.2 - Mailbox Full - Mailbox storage quota exceeded5.2.1 - Mailbox Disabled - Mailbox permanently disabled5.2.0 - Other Mailbox Status - Other mailbox-related issues452 4.2.1 Mailbox temporarily disabled
The recipient's mailbox is temporarily unavailable.
Gmail : "Mailbox temporarily unavailable"Outlook/Hotmail : "452 4.2.1 Mailbox temporarily disabled"Yahoo : "Mailbox temporarily not accepting messages"Enterprise : "Mailbox temporarily suspended"Don't Give Up Immediately : Unlike hard bounces, 4.2.1 bounces are temporary—retry sendingRespect Retry Limits : Don't retry indefinitely; set a maximum number of attemptsMonitor Patterns : Track recipients who frequently have disabled mailboxesConsider Alternative Channels : For important communications, consider using alternative contact methods if the mailbox remains disabledMaintain List Hygiene : Regularly clean your email list to remove addresses that consistently have disabled mailboxes