SMTP bounce code 5.4.3 indicates that an intermediate routing server has permanently failed and cannot forward messages. This is a permanent failure (hard bounce), meaning there's a persistent issue with the routing infrastructure that prevents message delivery.
The enhanced status code 5.4.3 follows the SMTP Enhanced Status Code format:
5 = Permanent failure (hard bounce)4 = Network and routing status3 = Routing server failureWhen you receive a 5.4.3 bounce, it means an intermediate mail server in the routing path has permanently failed and cannot forward your message. This is different from 4.4.3 (temporary) in that the routing server failure is permanent and won't resolve.
Type : Hard bounce (permanent failure)Category : Network/RoutingAction Required : Remove the email address from your mailing list or investigate routing alternativesRouting Server Permanently Down : An intermediate routing server has been permanently shut downServer Decommissioned : The routing server has been decommissioned and is no longer operationalPermanent Configuration Issues : Permanent misconfiguration of routing rules or server settingsDNS Permanently Invalid : DNS records point to routing servers that no longer existNetwork Infrastructure Failure : Permanent network infrastructure problems affecting routingMX Record Issues : MX records point to permanently unavailable routing serversRouting Server Migration : Routing server migration complete with old servers permanently offlineAbandoned Routing Infrastructure : The routing infrastructure has been abandonedPermanent Resource Exhaustion : Routing server has permanently exhausted resourcesCritical Routing Failure : Critical failure in routing infrastructure that cannot be resolvedRemove from List : Immediately remove the email address from your active mailing listVerify Domain Status : Check if the domain and routing infrastructure are still activeContact Recipient : If possible, contact the recipient through alternative channels to verify their mail routingDocument the Issue : Document which domains are affected by permanent routing failuresMonitor for Recovery : Periodically check if the issue has been resolved (though unlikely)Use Alternative Channels : For important communications, use alternative contact methodsRemove from Database : Immediately remove the email address from your sending databaseImplement Bounce Handling : Set up automated bounce processing to remove 5.4.3 bounces from your databaseCheck MX Records : Verify MX records to identify routing server issuesSuppression List : Add these addresses to a suppression list to prevent future send attemptsMonitor Domain Status : Periodically check if domains with 5.4.3 errors have resolved their issuesLog Routing Patterns : Track which routing servers are permanently failingDNS Validation : Validate DNS and MX records for affected domainsWhen you receive 5.4.3 bounces, investigate:
Check MX Records : Verify if MX records are valid and pointing to active routing serversTest Routing Path : Try to trace the routing path to identify failed serversVerify Domain Status : Check if the domain is still active and routing is configuredContact Support : Contact the recipient's IT department if possibleDocument Pattern : Document if multiple addresses from the same domain are affectedCheck Alternative Routes : See if alternative MX records provide working routes4.4.3 - Routing Server Failure - Temporary routing server failure5.4.1 - No Answer From Host (Permanent) - Permanent host unavailability5.4.2 - Bad Connection (Permanent) - Permanent connection failure5.4.4 - Unable to Route - Unable to determine routing path550 5.4.3 Routing server failure
Intermediate routing server permanently unavailable.
550 5.4.3 <[email protected] >: Routing server failure - intermediate server permanently down
Generic : "550 5.4.3 Routing server failure"Server Down : "Intermediate routing server permanently unavailable"MX Error : "Mail routing path includes permanently failed server"Infrastructure : "Routing infrastructure permanently unavailable"Never Retry : Don't attempt to resend emails to addresses that bounce with 5.4.3—they will continue to failRemove Immediately : Remove addresses with 5.4.3 bounces from your mailing list immediatelyVerify MX Records : Check MX records to understand routing configurationUse Suppression Lists : Maintain suppression lists to prevent sending to domains with routing failuresMonitor Domain Health : Track domains with permanent routing infrastructure issuesCheck Alternative Routes : Verify if alternative MX records provide working routesDocument Issues : Keep records of domains with permanent routing failuresContact Administrators : Contact domain administrators if routing issues affect important communicationsWhen investigating 5.4.3 bounces:
Check MX record priorities Verify all MX records are valid Test connectivity to each MX record Identify which routing servers have failed Understanding the routing path:
Trace the path from your server to destination Identify intermediate routing servers Determine which server in the path has failed Check if alternative routes exist