SMTP bounce code 5.4.1 indicates that the destination mail server is permanently not responding to connection attempts. This is a permanent failure (hard bounce), meaning the host is permanently unreachable and you should remove the email address from your mailing list.
The enhanced status code 5.4.1 follows the SMTP Enhanced Status Code format:
5 = Permanent failure (hard bounce)4 = Network and routing status1 = No answer from hostWhen you receive a 5.4.1 bounce, it means the mail server cannot establish a connection with the destination host because it's permanently unavailable. This is different from 4.4.1 (temporary) in that the host is confirmed to be permanently unreachable.
Type : Hard bounce (permanent failure)Category : Network/RoutingAction Required : Remove the email address from your mailing list immediatelyServer Permanently Down : The destination mail server has been permanently shut downHost No Longer Exists : The mail server host no longer exists or has been decommissionedDNS Permanently Invalid : DNS records point to a host that no longer existsNetwork Permanently Unreachable : The host is permanently unreachable due to network issuesServer Decommissioned : The mail server has been decommissioned and is no longer operationalAbandoned Infrastructure : The mail server infrastructure has been abandonedPermanent Firewall Blocking : Permanent firewall rules blocking all connectionsIP Address Deallocated : The IP address has been deallocated and is no longer in useServer Migration Complete : Server migration is complete and old servers are permanently offlineCritical Failure : Critical system failure that has permanently disabled the hostRemove from List : Immediately remove the email address from your active mailing listVerify Domain Status : Check if the domain and mail server are still activeContact Recipient : If possible, contact the recipient through alternative channels to verify their mail server statusDocument the Issue : Document which domains are affected by permanently unreachable hostsMonitor for Recovery : Periodically check if the issue has been resolved (though unlikely)Remove from Database : Immediately remove the email address from your sending databaseImplement Bounce Handling : Set up automated bounce processing to remove 5.4.1 bounces from your databaseDNS Validation : Verify DNS records to confirm host unavailabilitySuppression List : Add these addresses to a suppression list to prevent future send attemptsMonitor Domain Status : Periodically check if domains with 5.4.1 errors have resolved their issuesLog Host Patterns : Track which hosts are permanently unreachableWhen you receive 5.4.1 bounces, investigate:
Check DNS Records : Verify if MX records are valid and pointing to active serversTest Host Connectivity : Try to connect to the mail server host directlyVerify Domain Status : Check if the domain is still active and registeredContact Support : Contact the recipient's IT department if possibleDocument Pattern : Document if multiple addresses from the same domain are affected550 5.4.1 No answer from host
Host is permanently unreachable.
Generic : "550 5.4.1 No answer from host"Host Down : "Host permanently unreachable"Server Decommissioned : "Mail server no longer operational"DNS Error : "Host no longer exists in DNS"Never Retry : Don't attempt to resend emails to addresses that bounce with 5.4.1—they will continue to failRemove Immediately : Remove addresses with 5.4.1 bounces from your mailing list immediatelyUse Suppression Lists : Maintain suppression lists to prevent sending to permanently unreachable hostsVerify DNS : Check DNS records to confirm host unavailabilityMonitor Domain Health : Track domains with permanently unreachable mail serversContact Recipients : If possible, contact recipients through alternative channelsDocument Issues : Keep records of domains with permanent host unavailabilityReview Periodically : Periodically check if issues have been resolved (though unlikely for permanent failures)